Doctoral thesis about pathogenesis of avian influenza virus

On November 25 2011, Aida Chaves (PhD student of the CReSA) will defend her doctoral thesis entitled Study of the pathogenesis of highly pathogenic influenza A virus (H7N1) infection in chickens, with special focus in the central nervous system”, directed by Dr Natàlia Majó.

Highly pathogenic avian influenza viruses (HPAIV) cause a very severe systemic disease in chickens, in which is also frequent to find central nervous system (CNS) lesions. In this thesis, three studies were undertaken in order to determine the mechanism of pathogenesis, the neurotropism and establish the route of entry into the CNS use for a H7N1 HPAI virus. Results obtained underline the main function of the endothelial cells in the neuroinvasion by this H7N1 virus.

The event will be held on November 25 (12:00h), in the Sala de Graus of the Facultat de Veterinària (Universitat Autònoma de Barcelona).

To contact the author of this thesis:

Aida Chaves
PhD Student
Phone: +34 935814527
Fax: +34 93581490
08193 Bellaterra (Barcelona) Spain

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