One-dose vaccination of sows against PCV2 induces colostral antibody transfer

A study from CReSA investigated the presence of porcine circovirus type 2 (PCV2) DNA and antibody to the virus in the serum and colostrum of sows vaccinated prior to mating and in their offspring.

The study revealed that immunisation of sows with one dose of commercial PCV2 vaccine prior to mating induces a robust humoral response that results in the provision of high concentrations of homogeneous colostral antibody.

There is currently only one porcine circovirus type 2 (PCV2) vaccine specifically licensed for use in sows, and this is usually administered on two or more occasions prior to mating or farrowing. However, there is little information on the impact of vaccination on only one occasion prior to mating on PCV2 antibody concentrations in sow serum and colostrum. Subsequently, the objective of this study was to look for PCV2 DNA and antibody to this virus in the serum and colostrum of sows vaccinated prior to mating, and in their offspring.
The results indicated that vaccination prior to mating elicited a strong, homogeneous humoral response and, in consequence, more homogeneous colostral PCV2 antibody concentrations.

This paper has been recently published in: Sibila M, Fraile L, Ticó G, López-Soria S, Nofrarías M, Huerta E, Llorens A, López-Jiménez R, Pérez D, Segalés J. Humoral response and colostral antibody transfer following 'one-dose' pre-mating vaccination of sows against porcine circovirus type-2. Vet J. 2013 Sep;197(3):881-3.

Download the full paper (ScienceDirect): http://linkinghub.elsevier.com/retrieve/pii/S1090-0233(13)00185-8

Contact the first author of this paper:

Dr Marina Sibila Vidal
Researcher of CReSA
Email: marina.sibila@cresa.uab.cat
Phone no.: +34 93 581 44 95
Fax: +34 93 581 44 90
Campus de la UAB, Edifici CReSA, s/n
08193 Bellaterra (Cerdanyola del Vallès) Spain

 
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