Antimicrobial use as a risk factor associated with the emergence of cephalosporin resistance in Escherichia coli and Salmonella spp in pigs

The next December 13, 2016 the thesis of Karla Alejandra Cameron Veas will be presented in the Sala de Graus of the Veterinary School of the UAB. The thesis is entitled "Antimicrobial use as a risk factor associated with the emergence of cephalosporin resistance in Escherichia coli and Salmonella spp in pigs" and it is registered in the Department of Animal Health and Anatomy of the UAB. The project was directed by Dr. Lorenzo Fraile and Dra. Lourdes Migura a researcher at IRTA-CReSA, and supervised by Dr. Joaquim Segalés researcher at the IRTA-CReSA and professor of the Faculty of Veterinary Medicine at the UAB. 

Although cephalosporins are rarely used in pig farms, ceftiofur and cefquinome, a third and a fourth generation cephalosporins respectively, are licensed for treatment of systemic bacterial infections. The worrisome of extended spectrum cephalosporinases (ESC) producing Escherichia coli and Salmonella enterica entering the food chain have raised the debate on the use of these type of antimicrobials for animal husbandry.

The main objective of this thesis was to evaluate the association between management practices in relation with antimicrobial consumption in pig farms and the emergence of cephalosporin resistant (CR) E. coli and Salmonella. Moreover, the studies intended to elucidate if the farm was a reservoir of resistance genes harboured in transferable plasmids similar to those found in the community.

This work was funded by MINECO Proyecto AGL2011-28836: Assessment of risk factors in relation with antimicrobial consumption associated to the emergence of cephalosporin resistance in food animals.

To contactat with the director of this thesis:

Dra. Lourdes Migura 
IRTA-CReSA Researcher
Email: lourdes.migura@irta.cat
Phone: +34 93 467 40 40
Campus UAB, Edifici CReSA s/n,  08193  Bellaterra (Cerdanyola del Vallès) Spain

About IRTA:

IRTA is a research institute devoted to R+D+I in a variety of agri-food areas, such as vegetal production, animal production, food industries, environment and global change, and agri-food economy. The transfer of scientific advances contribute to the modernization, competitiveness and sustainable development of agriculture, food and aquaculture sectors, the supply of healthy and quality foods for consumers and, consequently, improving the welfare of the population. IRTA is assigned to the Departament d’Agricultura, Ramaderia, Pesca i Alimentació (DARP, Department of Agriculture) of the Generalitat de Catalunya (Government of Catalonia).

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